System leaders globally are aspiring toward a paradigm shift in education where a wider range of skills is achieved through new learning pathways. Such a shift requires a serious, disciplined and radical innovation at all levels of the system, and demands that governments rethink their roles in innovation eco-systems. This report aims to support system leaders in defining the potential benefits and the key drivers of system innovation in public services, as well as to identify the conditions that promote and inhibit it. The report draws recommendations for globally applicable policies, tools, frameworks, and indices that could stimulate changes in practice.